Detappe A. Process for conjugation-ratio-controlled release of conjugated proteins from hydrogel matrices, EP26300216.4, 2026 – patent licensed
Charbonnière L, Tsvetkov P, Detappe A, Zhu C, Mishra P, Selvaratnam A, Banerjee M, Ralahy B. Elesclomol derivatives and use thereof. EP26300125.7, 2026
Detappe A, Tillement O, David L, Tillement A, Belarouci E, Lux F, Grange C, Jacquot G. Pharmaceutical formulation comprising a protein and functionalized chitosan for subcutaneous administration. WO2026/008804, 2026 – Patent licensed
Detappe A, Ghosh S, Draussin J, Lopez Navarro P. Complexe peptidique radiosensibilisant. FR2042983, 2025
Detappe A, Grange C. Process for long-term storage of proteins. EP25306906, 2025
Tillement A, Tillement T, Tillement O, Lux F, David L, Duroux C, Rossetti F, Decker Y, Fassbender K, Labrune E, Salle B, Deutsch E, Morel D, Cassagnau P, Gillet P, Vourc’h M, Chevalier P, Pivot X, Detappe A. Procédé de diagnostic, pronostic et/ou de suivi thérapeutique de maladies impactant le profil minéral d’au moins un fluide biologique, ainsi qu’un dispositif, un système et un logiciel utiles pour sa mise en œuvre. FR2402722, 2024
Detappe A, Pivot X, Coliat P, Tillement O, Lux F, David L, Grea T. Pharmaceutical formulation for subcutaneous administration of proteins. WO2023/148351 A1, 2023 – patent licensed
Johnson JA, Nguyen HVTN, Jiang Y, Detappe A, Agius M, Ghobrial IM. Proteolysis targeting chimeric molecules (PROTACS) with functional handles and uses thereof. US 2021/0220391, 2021
Johnson JA, Nguyen HVTN, Jiang Y, Detappe A, Agius M, Ghobrial IM. Boronic ester prodrugs and uses thereof. US 2020/0369685A1, 2020 – patent licensed
Detappe A, Ghobrial IM, Reidy M, Ghoroghchian PP. B-cell Maturation Antigen (BCMA)-directed nanoparticles. WO2018/231949 A1, 2018 – patent licensed
Berbeco RI, Detappe A, Thomas E, Le Duc G, Lux F, Tillement O. Bismuth-gadolinium nanoparticles for MRI-guided radiation therapy. WO2018107057A1, 2018